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HIV kwenikweni zimitsani pa majini mlingo


2017-01-11 15:34:33

Mwa kusankha zina zomanga thupi ndi michere angapange HIV kupatsira maselo a chitetezo cha m`thupi kulowa "tulo" akafuna. Ichi ndi waukulu mapeto a Leora Weinberger ndi Thomas Shenk ya Princeton University.

Asayansi kumvetsa unyolo wa zamankhwala amuzolengedwa zochita zokhudza maselo chizindikiro amene amayambitsa HIV kuyamba kutengera lokha. A mbali yaikulu pa kukhazikitsidwa kwa HIV HIV kugawanika akuchita mapuloteni Tat. Ofufuza apeza gawo la tizilombo matupi athu akewo synthesis. Mwamwayi, ina yofunika chigawo chimodzi cha chizindikiro kubalana - enzyme p300, alipo T-lymphocytes. Kulumikizana Tat, ndipamene chomaliza uthenga.

Panthawiyi wina enzyme mu T selo, wotchedwa SirT1, wokhoza ziletsa synthesis wa Tat. Popeza tizilombo kugawanika lidzayamba pambuyo pa pakuoneka kuti si woyamba gulu la tinthu Tat ndi p300, ndi kudzikundikira ambiri amenewa mankhwala, ndi bwino pakati synthesis ndi SirT1 p300 ku maselo angakhale lophimba amene kudziwa kubalana wa HIV, kapena kupanda kwake.

Ngakhale kuti olemba ntchito ndiribe asanaganize zonse mwa mankhwala unyolo, koma mtima kwa gulu lonse, analemba membrana. Koma iwo amati, kulimbana ndi mabwenzi, inu mukhoza kulenga mankhwala kuti adzasunga izi lophimba mu "kutali" malo ndi HIV kukhala kungokhala chete.

Weinberger ananena kuti kupezeka n`kofunika, makamaka chifukwa chachikulu sayansi, koma anawonjezera kuti zingakhale zingayambitse mu khumi mankhwala atsopano amatha ngati sikuchiritsa munthu wa HIV matenda, koma kupondereza chulutsa HIV mu thupi .

Poyambirira, ndi njira, ngati muli ndi chibadwa lophimba ofufuza anapeza maselo a khansa. Ndipo ngakhale kutsimikiziridwa njira pa nyama.

Kuti HIV ndi chifukwa matenda - AIDS ofufuza akamufunsirire kuthana nawo mothandizidwa ambiri njira zatsopano Koma kumafuna kufufuza, chavuta ndi zina zachitukuko, ndicho kupalasa njinga: nyukiliya oteteza thupi, peputayidi anyani, edible katemera, mpendadzuwa, zobiriwira tiyi ngakhalenso immunodeficiency HIV wokha, koma zasinthidwa chibadwa.



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